Resumen: La inhibición de la RNA polimerasa II desencadena una respuesta de estrés celular que, de manera paradójica, conduce a la sobreexpresión de ciertos transcritos. Para explorar este fenómeno, realizamos ensayos genómicos en células humanas tratadas con triptolide (TPL), un inhibidor que altera la actividad translocasa de XPB, subunidad central del complejo TFIIH y que […]

Resumen de la plática In my presentation, I will discuss recent advancements from our laboratory in single cell phenomic analysis technologies. These include: 1) IRIS for ‘Interconnecting a Robotic Image of a cell to its ScRNA-seq profile’. This is a novel, so far unpublished technology that pairs the transcriptomic fingerprint of a single cell with […]

Resumen de la plática Plants are constantly surrounded by microbes in the soil, thereby shaping their fitness and soil environment. Among these, arbuscular mycorrhizal fungi (AM) have developed long-term partnerships with the plants since the beginning of land colonisation. Even now, 80% of land plants, including many crops, maintain this relationship, illustrating its diverse advantages […]