Resumen de la plática Los hongos del género Trichoderma son modelos que permiten entender la comunicación molecular entre microorganismos y plantas. En esta charla se abordará cómo tres tipos de compuestos secretados por Trichoderma —metabolitos secundarios, volátiles orgánicos y enzimas líticas— impactan el crecimiento de las plantas y el establecimiento de asociaciones simbióticas o patogénicas, […]

Resumen de la plática The capability to regenerate entire body parts is observed in some animals. Although they have the same basic bodyplan as other tetrapods, salamanders can regenerate many bodyparts including limbs, heart and the primary body axis. While these structures form during embryogenesis, the same structures must then regenerate at much larger scales. […]

Resumen de la plática Despite accounting for only 0.5% of the lung epithelium, pulmonary neuroendocrine (NE) cells give rise to a cancer type that accounts for a significant percentage of lung cancers (20 to 25%), including highly aggressive NE carcinomas and pulmonary NE tumors (carcinoids). The diversity of clinical behaviors displayed by these vastly understudied […]

Resumen de la plática The plant hormone auxin is a versatile endogenous signal influencing virtually all aspects of plant life. It has a unique ability to be directionally transported through tissues, forming local auxin maxima and gradients that are central to many developmental processes mediated by auxin. One of the key roles of auxin is […]

Aviso: el seminario del Dr De La Fuente se reprogamó para el martes 23 de septiembre a las 09:00 hora del Centro de México. Resumen de la plática For a century, antibiotic discovery has depended on labor-intensive “dirt mining”: scientists collected soil or water samples and painstakingly screening them for active compounds. That trial-and-error paradigm […]

Resumen: La inhibición de la RNA polimerasa II desencadena una respuesta de estrés celular que, de manera paradójica, conduce a la sobreexpresión de ciertos transcritos. Para explorar este fenómeno, realizamos ensayos genómicos en células humanas tratadas con triptolide (TPL), un inhibidor que altera la actividad translocasa de XPB, subunidad central del complejo TFIIH y que […]

Resumen de la plática In my presentation, I will discuss recent advancements from our laboratory in single cell phenomic analysis technologies. These include: 1) IRIS for ‘Interconnecting a Robotic Image of a cell to its ScRNA-seq profile’. This is a novel, so far unpublished technology that pairs the transcriptomic fingerprint of a single cell with […]