Resumen: La inhibición de la RNA polimerasa II desencadena una respuesta de estrés celular que, de manera paradójica, conduce a la sobreexpresión de ciertos transcritos. Para explorar este fenómeno, realizamos ensayos genómicos en células humanas tratadas con triptolide (TPL), un inhibidor que altera la actividad translocasa de XPB, subunidad central del complejo TFIIH y que […]

Resumen de la plática In my presentation, I will discuss recent advancements from our laboratory in single cell phenomic analysis technologies. These include: 1) IRIS for ‘Interconnecting a Robotic Image of a cell to its ScRNA-seq profile’. This is a novel, so far unpublished technology that pairs the transcriptomic fingerprint of a single cell with […]

Resumen de la plática Plants are constantly surrounded by microbes in the soil, thereby shaping their fitness and soil environment. Among these, arbuscular mycorrhizal fungi (AM) have developed long-term partnerships with the plants since the beginning of land colonisation. Even now, 80% of land plants, including many crops, maintain this relationship, illustrating its diverse advantages […]

Resumen de la plática Wild emmer wheat (Triticum turgidum subsp. dicccoides) stands among the earliest plant species to give rise to domesticated forms in the Fertile Crescent, approximately 11,000 years ago. Today, one of its descendants, bread wheat, is a staple crop of immense socio-economic importance, contributing to approximately 20% of the world's caloric intake. […]

Resumen de la plática Maize domestication is one of the most extreme examples of human-driven selection. Originating from a grass native to Mesoamerica around ten thousand years ago, maize underwent significant morphological transformations that obscured its origins for nearly a decade. Understanding the dispersion routes, admixture patterns, and the sequence of changes that led tomaize […]