Frontiers in Genomics: James Galagan
A neural network for quantitative biophysical transcription factor binding site design
Frontiers in Genomics: James Galagan
A neural network for quantitative biophysical transcription factor binding site design
Resumen de la ponencia High throughput genomic methods, such as ChIP-Seq, have greatly expanded our knowledge of transcription factor (TF) binding to DNA. A frequent observation is the presence of binding sites for individual TFs that span a wide range of apparent affinities. A quantitative biophysical understanding of the basis of TF binding strength is […]
