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Documentos Frontiers 2011-01

Modeling for the post-genomic ageWalter FontanaInternal coarse-graining of molecular systems | Intrinsic information carriers in combinatorial dynamical systems | Rule-Based Modelling of Cellular Signalling
Proteome Scale Prediction of Protein-Protein Interactions Using Interface StructuresRuth NussinovPrinciples of Protein-Protein Interactions: What are the Preferred Ways For Proteins To Interact? | Allostery and population shift in drug discovery | Conformational ensembles, signal transduction and residue hot spots: Application to drug discovery | Towards inferring time dimensionality in protein–protein interaction networks by integrating structures: the p53 example
Human population structure in the genomics era: Geography, admixture, and rare allelesJohn NovembreFast model-based estimation of ancestry in unrelated individuals | Principal Component Analysis under Population Genetic Models of Range Expansion and Admixture | Genes mirror geography within Europe | Supplementary Information for: Genes mirror geography within Europe
Elucidating the Symbiotic Signaling Pathway in LegumesDouglas CookEstimating genome conservation between crop and model legume species | The Medicago truncatula ortholog of Arabidopsis EIN2, sickle, is a negative regulator of symbiotic and pathogenic microbial associations | The symbiotic ion channel homolog DMI1 is localized in the nuclear membrane of Medicago truncatula roots | Identification of legume RopGEF gene families and characterization of a Medicago truncatula RopGEF mediating polar growth of root hairs
Building Atlases Using Genetics and Light MicroscopyEugene MyersDevelopment-Based Compartmentalization of the Drosophila Central Brain | A 3D digital atlas of C. elegans and its application to single-cell analyses | Reconstruction of Zebrafish Early Embryonic Development by Scanned Light Sheet Microscopy
The Molecular HuntEske Willerslev
Making a brain: a molecular dissection of neural inductionClaudio SternChurchill, a Zinc Finger Transcriptional Activator, Regulates the Transition between Gastrulation and Neurulation | A Mechanism Regulating the Onset of Sox2 Expression in the Embryonic Neural Plate | Initiation of neural induction by FGF signalling before gastrulation | Neural induction: old problem, new findings, yet more questions
[CANCELADO] Non-coding RNAs and their impact in plant developmentMartin CrespiNovel long non-protein coding RNAs involved in Arabidopsis differentiation and stress responses | Non-Protein-Coding RNAs and their Interacting RNA-Binding Proteins in the Plant Cell Nucleus | Genome-Wide Medicago truncatula Small RNA Analysis Revealed Novel MicroRNAs and Isoforms Differentially Regulated in Roots and Nodules
Guarding the genome: centromeres, aneuploidy and tumorigenesisDon ClevelandCentromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP | Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E | Aneuploidy Acts Both Oncogenically and as a Tumor Suppressor
Epigenetic vulnerabilities in acute myeloid leukemiaChristopher VakocMouse models of human AML accurately predict chemotherapy response | Selective inhibition of BET bromodomains | T oolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi | MLL translocations, histone modifications and leukaemia stem-cell development
Deep Mutational Screening to Analyze Protein FunctionStan FieldsH igh-resolution mapping of protein sequence-function relationships