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Documentos Frontiers 2010-02

Cancer Gene Discovery in Mouse and ManDavid J. AdamsWhole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality | Novel Candidate Cancer Genes Identified by a Large-Scale Cross-Species Comparative Oncogenomics Approach | Large-Scale Mutagenesis in p19ARF- and p53-Deficient Mice Identifies Cancer Genes and Their Collaborative Networks
Heterochromatin and RNA interference in cell division and transposon regulationRobert MartienssenArgonaute Slicing Is Required for Heterochromatic Silencing and Spreading | Control of female gamete formation by a small RNA pathway in Arabidopsis
Tools for analyzing the human microbiomRobert KnightBacterial Community Variation in Human Body Habitats Across Space and Time | Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample
Genetic diversity and malaria drug and vaccine efficacyChristopher PloweThe Potential Role of Vaccines in the Elimination of Falciparum Malaria and the Eventual Eradication of Malaria | Extreme Polymorphism in a Vaccine Antigen and Risk of Clinical Malaria: Implications for Vaccine Development
Programming cellular behavior with RNA controllersChristina D. SmolkeHigher-Order Cellular Information Processing with Synthetic RNA Devices | Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems
TET proteins, enzymes that convert 5-methylcytosine to 5-hydroxymethylcytosine in DNAAnjana RaoConversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
A CNV based approach to gene discovery in neuropsychiatric disordersJonathan SebatMicroduplications of 16p11.2 are associated with schizophrenia | Rare structural variants in schizophrenia: one disorder, multiple mutations; one mutation, multiple disorders | Strong Association of De Novo Copy Number Mutations with Autism | Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia
Logic and Illusion in the Evolution of Drosophila Regulatory SequencesMichael EisenBinding Site Turnover Produces Pervasive Quantitative Changes in Transcription Factor Binding between Closely Related Drosophila Species | Sepsid even-skipped Enhancers Are Functionally Conserved in Drosophila Despite Lack of Sequence Conservation | Evolutionary Mirages: Selection on Binding Site Composition Creates the Illusion of Conserved Grammars in Drosophila Enhancers
Controls of germline stem cells and their differentiationJudith KimbleProgression from a stem cell–like state to early differentiation in the C. elegans germ line | Chemical reprogramming of Caenorhabditis elegans germ cell fate
[CANCELADO]Corinne Houart
Genomic and Metagenomic Insighs into the Microbial WorldJames TiedjeThe bacterial species definition in the genomic era | Comparative systems biology across an evolutionary gradient within the Shewanella genus
Phospholipid Signalling in Plant Stress and DevelopmentTeun MunnikHeat stress activates phospholipase D and triggers PIP2 accumulation at the plasma membrane and nucleus | Multiple PLDs Required for High Salinity and Water Defi cit Tolerance in Plants