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Documentos Frontiers 2009-02

Information Integration Approaches to Discovering Biology in Genomic DataJohn QuackenbushExtracting biology from high-dimensional biological data | What would you do if you could sequence everything? | Inferring steady state single-cell gene expression distributions from analysis of mesoscopic samples | Microarray Analysis and Tumor Classification | Seeded Bayesian Networks: Constructing genetic networks from microarray data
Our Approaches to design functional genomesMitsuhiro ItayaCombining two genomes in one cell: Stable cloning of the Synechocystis PCC6803 genome in the Bacillus subtilis 168 genome | Bottom-up genome assembly using the Bacillus subtilis genome vector
Next generation sequence database homology searches: theory, methods, and softwareSean EddyA Probabilistic Model of Local Sequence Alignment That Simplifies Statistical Significance Estimation
Genome instability as a result of transcription and replicationAndrés AguileraGenome instability: a mechanistic view of its causes and consequences | Genome-Wide Analysis of Factors Affecting Transcription Elongation and DNA Repair: A New Role for PAF and Ccr4-Not in Transcription-Coupled Repair
The genome diversity revolution: olfaction as a modelDoron LancetHigh-Resolution Copy-Number Variation Map Reflects Human Olfactory Receptor Diversity and Evolution | Human olfaction: from genomic variation to phenotypic diversity
The genes that were missed: an expanding universe of small RNAs and small proteinsGisela StorzRegulatory RNAs in Bacteria | Small membrane proteins found by comparative genomics and ribosome binding site models
Computational analysis of large-scale proteomic data: Current approaches, tools, and challengesBenno SchwikowskiSignal Maps for Mass Spectrometry-based Comparative Proteomics | Integration of biological networks and gene expression data using Cytoscape | An evolutionary and functional assessment of regulatory network motifs
The biodiversity within microbial species: population genetics and strain microevolutionSylvain BrisseVirulent Clones of Klebsiella pneumoniae: Identification and Evolutionary Scenario Based on Genomic and Phenotypic Characterization | A New Perspective on Listeria monocytogenes Evolution
Mapping connections between the genome, ionome and the physical landscapeDavid E. SaltRoot Suberin Forms an Extracellular Barrier That Affects Water Relations and Mineral Nutrition in Arabidopsis | Genomic scale profiling of nutrient and trace elements in Arabidopsis thaliana | Natural Variants of AtHKT1 Enhance Naþ Accumulation in Two Wild Populations of Arabidopsis
Studying cancer biology using RNA interference in vivoScott LoweTissue-specific and reversible RNA interference in transgenic mice | An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer
Metabolomics, a tool for gene discovery with huge potential for crop improvementAlisdair FernieMetabolite profiling: from diagnostics to systems biology | Metabolomics-assisted breeding: a viable option for crop improvement? | Natural genetic variation for improving crop quality | Comprehensive metabolic profiling and phenotyping of interspecific introgression lines for tomato improvement
Evolution of bacterial endosymbionts in insectsNancy A. MoranHamiltonella defensa, genome evolution of protective bacterial endosymbiont from pathogenic ancestors | Symbiosis as an adaptive process and source of phenotypic complexity | The Dynamics and Time Scale of Ongoing Genomic Erosion in Symbiotic Bacteria
[CANCELADO] Single-molecule analysis of transcriptionRichard H. EbrightInitial Transcription by RNA Polymerase Proceeds Through a DNA-Scrunching Mechanism | Abortive Initiation and Productive Initiation by RNA Polymerase Involve DNA Scrunching